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Can I read Quantifying Medial Temporal Lobe Damage in Memory-impaired Patients on EtoBox?
Quantifying Medial Temporal Lobe Damage in Memory-impaired Patients by Jeffrey J. Gold; Larry R. Squire is a Neuroscience article available to read on EtoBox.
What is Quantifying Medial Temporal Lobe Damage in Memory-impaired Patients about?
Studies of memory-impaired patients will be most useful when quantitative neuroanatomical information is available about the patients being studied. Toward that end, in the case of medial temporal lobe amnesia, protocols have been developed from histological material that identify the boundaries of relevant structures on magnetic resonance images. Because the size of these structures varies considerably in the normal population, some correction for overall brain size is usually employed when calculating volume measurements. Although different correction procedures have been used to normalize for brain size, there has been little study of how well different methods reduce variability and which methods might be most useful. We measured the volume of the hippocampal region (hippocampus proper, dentate gyrus, and subicular complex) and the volumes of the temporopolar, entorhinal, perirhinal, and parahippocampal cortices in five memory-impaired patients and 30 controls. We then compared three different methods for normalizing the volume measurements: normalization by intracranial volume, normalization by aligning the brain to a standard atlas, and normalization by brain area at the leve
Who reads Quantifying Medial Temporal Lobe Damage in Memory-impaired Patients?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Jeffrey J. Gold; Larry R. Squire
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1050-9631)
- Published
- 2005
- Language
- EN
- Field
- Neuroscience (Life Sciences)