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Isolated neck recurrence after definitive radiotherapy for node-positive head and neck cancer: Salvage in the dissected or undissected neck by Stanley L. Liauw; Robert J. Amdur; Christopher G. Morris; John W. Werning; Douglas B. Villaret; William M. Mendenhall is a Medicine article available to read on EtoBox.

What is Isolated neck recurrence after definitive radiotherapy for node-positive head and neck cancer: Salvage in the dissected or undissected neck about?

## Abstract ## Background. The role of salvage neck dissection for isolated regional recurrences after definitive radiotherapy (RT) is ill‐defined. ## Methods. Five‐hundred fifty patients were treated with RT for lymph node–positive head and neck cancer. RT consisted of a median dose of 74.4 Gy. Chemotherapy was administered in 133 patients (24%). Patients were followed for neck failure after planned neck dissection (__n__ = 341) or observation (__n__ = 209). Salvage therapy was offered to those with isolated neck recurrences. ## Results. There were 54 (10%) failures in the neck at a median 3.7 months after RT (range, 0 to 17 months). Thirteen patients had isolated recurrences after receiving definitive RT with (__n__ = 11) or without (__n__ = 2) neck dissection. Nine patients underwent attempted surgical salvage with or without re‐irradiation and 4 were successfully salvaged without major complications. ## Conclusions. Patients with neck failure after definitive therapy usually have poor outcomes, but salvage attempts may be successful in selected patients with an isolated neck recurrence. © 2007 Wiley Periodicals, Inc. Head Neck 2007

Who reads Isolated neck recurrence after definitive radiotherapy for node-positive head and neck cancer: Salvage in the dissected or undissected neck?

Author

Stanley L. Liauw; Robert J. Amdur; Christopher G. Morris; John W. Werning; Douglas B. Villaret; William M. Mendenhall

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1043-3074)

Published

2007

Language

EN

Field

Medicine (Health Sciences)