Opening book details…
Can I read Kinetics of Recombinant Immunoglobulin Production by Mammalian Cells in Continuous Culture on EtoBox?
Kinetics of Recombinant Immunoglobulin Production by Mammalian Cells in Continuous Culture by David K. Robinson; Klaus W. Memmert is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Kinetics of Recombinant Immunoglobulin Production by Mammalian Cells in Continuous Culture about?
A clonal derivative of a transfectant of the SP2/0 myeloma cell line producing a chimeric monoclonal antibody was maintained in steady-state, continuous culture at dilution rates ranging from 0.21 to 1.04 day-'. The steady-state values for nonviable and total cell concentrations increased as the dilution rate decreased, while the viable cell concentration was roughly independent of the dilution rate. At steady state, the specific growth rate increased and the specific death rate decreased as the dilution rate increased. The maximum specific growth rate was 1.15 day-'. Antibody production was growth associated and the specific rate of antibody production increased linearly as the specific growth rate increased.
Who reads Kinetics of Recombinant Immunoglobulin Production by Mammalian Cells in Continuous Culture?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- David K. Robinson; Klaus W. Memmert
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley - V C H Verlag GmbbH & Co.; Wiley (ISSN 0006-3592)
- Published
- 1991
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)