Can I read Primary Hyperparathyroidism and Fracture Probability on EtoBox?

Primary Hyperparathyroidism and Fracture Probability by John A. Kanis; Nicholas C. Harvey; Enwu Liu; Liesbeth Vandenput; Mattias Lorentzon; Eugene V. McCloskey; Roger Bouillon; Bo Abrahamsen; Lars Rejnmark; Helena Johansson; Tanja Sikjær; Lars Rolighed; Mette Friberg Hitz; Pia Eiken; Anne Pernille Hermann; Jens-Erik Beck Jensen; Lise Sofie Bislev; the Danish Primary Hyperparathyroidism Study Group is a Medicine article available to read on EtoBox.

What is Primary Hyperparathyroidism and Fracture Probability about?

The incidence of hip and major osteoporotic fracture was increased in patients with primary hyperparathyroidism even in patients not referred for parathyroidectomy. The risk of death was also increased which attenuated an effect on fracture probabilities. The findings argue for widening the indications for parathyroidectomy in mild primary hyperparathyroidism. Introduction Primary hyperparathyroidism (PHPT) is associated with an increase in the risk of fracture. In FRAX, the increase in risk is assumed to be mediated by low bone mineral density (BMD). However, the risk of death is also increased and its effect on fracture probability is not known. Objective The aim of this study was to determine whether PHPT affects hip fracture and major osteoporotic fracture risk independently of bone mineral density (BMD) and whether this and any increase in mortality affects the assessment of fracture probability. Methods A register-based survey of patients with PHPT and matched controls in Denmark were identified from hospital registers. The incidence of death, hip fracture, and major osteoporotic fracture were determined for computing fracture probabilities excluding time after parathyroidect

Who reads Primary Hyperparathyroidism and Fracture Probability?

Author

John A. Kanis; Nicholas C. Harvey; Enwu Liu; Liesbeth Vandenput; Mattias Lorentzon; Eugene V. McCloskey; Roger Bouillon; Bo Abrahamsen; Lars Rejnmark; Helena Johansson; Tanja Sikjær; Lars Rolighed; Mette Friberg Hitz; Pia Eiken; Anne Pernille Hermann; Jens-Erik Beck Jensen; Lise Sofie Bislev; the Danish Primary Hyperparathyroidism Study Group

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)