Can I read Design of Water-based Ferrofluids as Contrast Agents for Magnetic Resonance Imaging on EtoBox?

Design of Water-based Ferrofluids as Contrast Agents for Magnetic Resonance Imaging by Maria F. Casula; Anna Corrias; Paolo Arosio; Alessandro Lascialfari; Tapas Sen; Patrizia Floris; Ian J. Bruce is a Chemistry article available to read on EtoBox.

What is Design of Water-based Ferrofluids as Contrast Agents for Magnetic Resonance Imaging about?

We report the synthesis, characterization and relaxometric study of ferrofluids based on iron oxide, with potential for use as magnetic resonance imaging (MRI) contrast agents (CAs). The effect of different costeffective, water-based surface modification approaches which can be easily scaled-up for the large scale synthesis of the ferrofluids has been investigated. Surface modification was achieved by silanization, and/ or coating with non-toxic commercial dispersants (a lauric polysorbate and a block copolymer with pigment affinic groups, namely Tween 20 and Disperbyk 190) which were added after or during iron oxide nanoparticle synthesis. It was observed that all the materials synthesized functioned as negative contrast agents at physiological temperature and at frequencies covered by clinical imagers. The relaxometric properties of the magnetic nanoparticles were significantly improved after surface coating with stabilizers compared to the original iron oxide nanoparticles, with particular reference to the silica-coated magnetic nanoparticles. The results indicate that the optimization of the preparation of colloidal magnetic ferrofluids by surface modification is effective in t

Who reads Design of Water-based Ferrofluids as Contrast Agents for Magnetic Resonance Imaging?

Author

Maria F. Casula; Anna Corrias; Paolo Arosio; Alessandro Lascialfari; Tapas Sen; Patrizia Floris; Ian J. Bruce

Publisher

Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0021-9797)

Published

2011

Language

EN

Field

Chemistry (Physical Sciences)