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What is Pseudomonas Aeruginosa: Piperacillin-Tazobactam Breakpoints For about?

This document discusses revising piperacillin-tazobactam breakpoints for Pseudomonas aeruginosa based on new pharmacokinetic and clinical data. It reviews the FDA-approved dosing schedules and commonly used dosages of piperacillin-tazobactam. Studies using modern pharmacokinetic/pharmacodynamic methods highlight low probability of target attainment at MICs >16 μg/mL. The CLSI working group evaluated available evidence to possibly revise breakpoints against P. aeruginosa.

Author

Alonso Antonio Arroyo

Language

EN