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What is Functional Nucleic Acids and Evolution about?

This document discusses the possibility that early life may have emerged from mixtures of chemically diverse nucleic acid building blocks, rather than from a single well-defined genetic polymer like RNA. It suggests that functional nucleic acid structures could evolve despite nonheritable variations in backbone structure through replication and selection. The authors tested this by selecting for RNA/DNA mosaic aptamers that bind nucleotide ligands using in vitro selection. They were able to isolate ATP- and

Author

Vlad Preda

Language

EN