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Can I read Cytomegalovirus Infection: the Point in 2001 on EtoBox?
Cytomegalovirus Infection: the Point in 2001 by D Salmon-Ceron is a Medicine article available to read on EtoBox.
What is Cytomegalovirus Infection: the Point in 2001 about?
The incidence of cytomegalovirus (CMV) disease, one of the most prevalent opportunistic infections in HIV‐infected persons in the early 1990s, has decreased by more than 80% since the introduction of highly active antiretroviral therapy (HAART). The rare cases of CMV disease still observed in Western countries occur mainly in profoundly immunosuppressed patients who have failed to respond to HAART. A new finding is the occasional occurrence of inflammatory retinitis in some patients on HAART with a history of healed retinitis. New tools for CMV detection have become available recently, including use of polymerase chain reaction (PCR) to detect CMV DNA from plasma. It has been possible to redefine, in the HAART period, patients at risk for CMV disease as those who have a low CD4 cell count as well as a blood marker of CMV blood dissemination (plasma CMV DNAaemia or high pp65 antigenaemia). Besides the classical therapeutic approach using ganciclovir (GCV), foscarnet and cidofovir, development of valganciclovir (VGCV), an orally administered prodrug of GCV, appears promising. There is evidence to suggest that it is as effective as intravenous GCV for the treatment of CMV retinitis, a
Who reads Cytomegalovirus Infection: the Point in 2001?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- D Salmon-Ceron
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1464-2662)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)