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Short- and Long-Term Effects of Bariatric Surgery on Vascular Phenotype by Lukas Streese; Karsten Königstein; Lara Goricki; Denis Infanger; Bettina Wölnerhanssen; Thomas Peters; Arno Schmidt-Trucksäss; Henner Hanssen is a Medicine article available to read on EtoBox.

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## Background: Retinal microvascular diameters and large artery stiffness are valid biomarkers of cardiovascular risk. this study assessed short- and long-term micro- and macrovascular improvements after bariatric surgery (bs). ## Methods: Sixteen patients (44 ± 12 years) underwent bs in this observational study. two weeks before as well as 6 weeks and 4 years after surgery, retinal vessel analysis and assessment of brachial-ankle pulse wave velocity (bapwv), cardio-ankle vascular index (cavi), and anthropometry were performed. three patients were lost to follow-up. ## Results: Six weeks after bs, retinal arteriolar diameters (crae) were wider (180.1 μm vs. 188.1 μm; p = 0.001), and the arteriolar-to-venular diameter ratio (avr) was higher (0.82 vs. 0.86; p < 0.001) compared to baseline levels. during the 4 years of follow-up, the retinal changes sustained but further improvements did not occur. both indices of large artery stiffness, bapwv and cavi, remained unchanged 6 weeks and 4 years after surgery. ## Conclusions: Retinal microvascular phenotype improved 6 weeks after bs. the improvements in microvascular health were maintained during 4 years of follow-up but, despite signific

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Author

Lukas Streese; Karsten Königstein; Lara Goricki; Denis Infanger; Bettina Wölnerhanssen; Thomas Peters; Arno Schmidt-Trucksäss; Henner Hanssen

Published

2019

Language

EN

Field

Medicine (Health Sciences)