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Vascular dysfunction and body mass index in African adults with HIV by Longa Kaluba; Theresa Chikopela; Fastone Goma; Mordecai Malambo; Wilbroad Mutale; Douglas C. Heimburger; John R. Koethe is a Medicine article available to read on EtoBox.

What is Vascular dysfunction and body mass index in African adults with HIV about?

Abstract Background Impaired vascular compliance is common among persons with HIV (PWH) and a risk factor for cardiovascular disease (CVD), though many studies documenting this are from regions with a high prevalence of overweight and obesity. The prevalence and characteristics of impaired vascular compliance among PWH with low body mass index (BMI) is not well described, particularly in sub-Saharan Africa (SSA) where the majority of PWH live, a low BMI is more common, and the burden of CVD is rising. Aim To assess non-invasive vascular compliance measurements, including augmentation index (AIX), pulse wave velocity (PWV) and pulse waveforms, in underweight, normal weight, and overweight PWH on long-term antiretroviral therapy (ART) in SSA. Methods A cross-sectional study among PWH on ART at the University Teaching Hospital in Lusaka, Zambia. All participants had been on a regimen of efavirenz, emtricitabine, and tenofovir disoproxil fumarate for five or more years. Carotid-femoral PWV (cfPWV), carotid-radial PWV (crPWV), and the corresponding augmentation indexes (cfAIX and crAIX), were measured in all participants, in addition to aortic pressure waveforms, classified as type A, B

Who reads Vascular dysfunction and body mass index in African adults with HIV?

Author

Longa Kaluba; Theresa Chikopela; Fastone Goma; Mordecai Malambo; Wilbroad Mutale; Douglas C. Heimburger; John R. Koethe

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)