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This document provides a comprehensive guide on the synthesis of ketamine, detailing various procedures and techniques, including reagent preparation and the synthesis of the ketone precursor. It emphasizes the importance of temperature control and purification methods to achieve high yields while warning against the dangers involved in the synthesis process. The guide includes both Friedel-Crafts and Grignard reaction methods for creating the key ketone compound, along with insights into their relative adv

Author

Tony Cortese

Language

EN