Skip to content

Opening book details…

Can I read Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery on EtoBox?

Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery by Lunz, Andre (author);Knappe, Kevin (author);Omlor, Georg W. (author);Schonhoff, Mareike (author);Renkawitz, Tobias (author);Jaeger, Sebastian (author) is a Medicine article available to read on EtoBox.

What is Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery about?

## Abstract ## Background Antibiotic-loaded polymethylmethacrylate (PMMA) bone cement spacers provide high local antibiotic concentrations and patient mobility during the interim period of two-stage revision for periprosthetic joint infection (PJI). This study compares mechanical characteristics of six dual antibiotic-loaded bone cement (dALBC) preparations made from three different PMMA bone cements. The study`s main objective was to determine the effect of time and antibiotic concentration on mechanical strength of dALBCs frequently used for spacer fabrication in the setting of two-stage revision for PJI. ## Methods A total of 84 dual antibiotic-loaded bone cement specimens made of either Copal spacem, Copal G + V or Palacos R + G were fabricated. Each specimen contained 0.5 g of gentamicin and either 2 g (low concentration) or 4 g (high concentration) of vancomycin powder per 40 g bone cement. The bending strength was determined at two different timepoints, 24 h and six weeks after spacer fabrication, using the four-point bending test. ## Results Preparations made from Copal G + V showed the highest bending strength after incubation for 24 h with a mean of 57.6 ± 1.2 MPa (low co

Who reads Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Lunz, Andre (author);Knappe, Kevin (author);Omlor, Georg W. (author);Schonhoff, Mareike (author);Renkawitz, Tobias (author);Jaeger, Sebastian (author)
Publisher
Springer Science and Business Media LLC
Published
2022
Language
EN
Field
Medicine (Health Sciences)

More by Lunz, Andre (author);Knappe, Kevin (author);Omlor, Georg W. (author);Schonhoff, Mareike (author);Renkawitz, Tobias (author);Jaeger, Sebastian (author)

Browse all works by Lunz, Andre (author);Knappe, Kevin (author);Omlor, Georg W. (author);Schonhoff, Mareike (author);Renkawitz, Tobias (author);Jaeger, Sebastian (author)