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What is CXCL13: Target in Inflammatory Diseases about?

CXCL13 is a chemokine crucial for the regulation of secondary lymphoid organs and is implicated in various immune-mediated inflammatory diseases. In healthy conditions, it is primarily secreted by stromal cells and follicular helper T cells, while in disease states, ectopic expression occurs from peripheral helper T cells and macrophages, influencing immune cell migration and inflammatory responses. This review highlights the potential of targeting CXCL13 for therapeutic strategies in treating immune-mediat

Author

yeraygranado

Language

EN