Can I read The Role of Allergy in the Development of Asthma on EtoBox?

The Role of Allergy in the Development of Asthma by P. G. Holt; C. Macaubas; P. A. Stumbles; P. D. Sly is a Physics and Astronomy article available to read on EtoBox.

What is The Role of Allergy in the Development of Asthma about?

Recent studies have shown that initial sensitization to airborne environmental allergens occurs typically in early childhood, but subsequent progression to persistent atopic asthma, which may not manifest for several years, is restricted to only a subset of atopics. The key to establishing the link between atopy and asthma lies in the development of persistent in ̄ammation in the airway wall, resulting in structural and functional changes in local tissues which are responsible for the symptoms of the disease. This review summarizes recent ®ndings on the nature of the cellular and molecular mechanisms underlying this process, and addresses the issue of why the intensity and duration of these tissue-damaging responses in the airway wall apparently exceeds the critical threshold required for development of persistent asthma in only a minority of allergy sufferers.

Who reads The Role of Allergy in the Development of Asthma?

Author

P. G. Holt; C. Macaubas; P. A. Stumbles; P. D. Sly

Publisher

Springer Science and Business Media LLC

Published

1999

Language

EN

Field

Physics and Astronomy (Physical Sciences)