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The mechanism of action of insulin involves binding to insulin receptors on cells, which stimulates the phosphorylation of intracellular substrates and initiates two metabolic pathways. Sulfonylureas stimulate insulin secretion by inhibiting potassium channels in beta cells, while meglitinides block potassium channels similarly. Biguanides reduce gluconeogenesis by activating the enzyme AMPK in the liver. The inhibitors...

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