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Ugi Reaction for Proline-like N-Aminolactams by Kishore Kumar is a document available to read on EtoBox.

What is Ugi Reaction for Proline-like N-Aminolactams about?

1. A Ugi reaction involving keto acids, protected hydrazines, and isocyanides provides a simple method to access cyclic N-aminolactam products. 2. The N-aminolactam products form a consistent intramolecular hydrogen bond, leading to a beta-turn-like secondary structure. 3. This reaction design allows the integration of N-aminolactam units into pseudopeptide fragments without disrupting the folded structure.

Author

Kishore Kumar

Language

EN