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This study evaluates incomplete chromosome aberrations induced by alpha-particle irradiation in human lymphocytes using pan-centromeric and pan-telomeric probes. A total of 378 incomplete chromosomes were identified, with a significant number of acentric fragments categorized by their lengths. The findings suggest that alpha-particle exposure results in a higher percentage of incomplete rejoinings compared to low-LET radiation, indicating a different repair mechanism for centromere-containing elements.

Author

Sherlocky

Language

EN