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Can I read Corneal Ulcer in Dogs and Cats: Novel Clinical Application of Regenerative Therapy Using Subconjunctival Injection of Autologous Platelet-Rich Plasma on EtoBox?
Corneal Ulcer in Dogs and Cats: Novel Clinical Application of Regenerative Therapy Using Subconjunctival Injection of Autologous Platelet-Rich Plasma by Haithem A. Farghali; Naglaa A. AbdElKader; Huda O. AbuBakr; Eman S. Ramadan; Marwa S. Khattab; Noha Y. Salem; Ibrahim A. Emam is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Corneal Ulcer in Dogs and Cats: Novel Clinical Application of Regenerative Therapy Using Subconjunctival Injection of Autologous Platelet-Rich Plasma about?
**Background:** Corneal ulcer could be a major source of distress in small animals, with many contributing agents. In recent years, few studies evaluated the efficacy of platelet-rich plasma (PRP) in healing corneal ulcers. **Aim:** This study aimed to assess the ability of subconjunctival injection of autologous PRP in the treatment of corneal ulcers in dogs and cats as well as estimate the expression of matrix metalloproteinase (MMP)-2, MMP-9, and oxidative stress biomarkers in these patients. **Methods:** A total number of 28 animals (16 cats and 12 dogs) were enrolled in this study. Each animal was subjected to clinical, neurologic, and ophthalmic examinations where the type of ulcer was documented. Tear samples were collected for evaluation of oxidative biomarkers and MMPs; conjunctival swabs were taken to identify the involved organism. PRP was prepared from each animal and given as subconjunctival injection; numbers of injections were done according to case response. Clinical follow-up was done and documented for each case. **Results:** In cat patients, female and Persian cats were most affected; unilateral and superficial ulcers were most recorded. In male dogs, unilateral,
Who reads Corneal Ulcer in Dogs and Cats: Novel Clinical Application of Regenerative Therapy Using Subconjunctival Injection of Autologous Platelet-Rich Plasma?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Haithem A. Farghali; Naglaa A. AbdElKader; Huda O. AbuBakr; Eman S. Ramadan; Marwa S. Khattab; Noha Y. Salem; Ibrahim A. Emam
- Publisher
- Frontiers Media SA
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)