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What is Advances in Isothermal Titration Calorimetry about?
This document discusses isothermal titration calorimetry (ITC), a technique that directly measures the heat released or absorbed by the stepwise addition of a ligand molecule to a solution containing a macromolecule. ITC allows the direct determination of binding constants, numbers of binding sites, and the associated enthalpic and entropic contributions to binding. Recent advances in highly sensitive microcalorimetry instruments have expanded the range of applications of ITC by enabling measurement of even
- Author
- Alan R. F. K. Moraes
- Language
- EN