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This document presents a study comparing three superdisintegrants - sodium starch glycolate, croscarmellose, and crospovidone - for their effectiveness in formulating orally disintegrating tablets of the antiemetic drug promethazine HCl. Nine formulations were prepared using these superdisintegrants at different concentrations and evaluated for various parameters. The results showed that tablets formulated with crospovidone exhibited the fastest drug release compared to the other superdisintegrants.

Author

Lina Winarti

Language

EN