Can I read Cancer Stem Cells: Methods and Protocols (Methods in Molecular Biology (568)) on EtoBox?

Cancer Stem Cells: Methods and Protocols (Methods in Molecular Biology (568)) by John S. Yu (editor) is a nonfiction available to read on EtoBox.

What is Cancer Stem Cells: Methods and Protocols (Methods in Molecular Biology (568)) about?

Cancer is a devastating disease that affects millions of people in the world. Our the- pies for tumors have mostly been based on classical chemotherapy and antiproliferative treatments. More recently, directed therapies against a causative oncogene have led to prominent reduction in tumor rates for some cancers. For instance, chronic myelogenous leukemia that is due to a BCR–ABL translocation can be targeted with Gleevec. Despite these advances in individual tumors, a number of patients are treated for their primary tumors and ultimately relapse. Relapsing tumors can be due to resistance to chemotherapy or to antioncogene drugs. Another hypothesis is that heterogeneity in the tumor leads to an inability of classical chemotherapy to completely eradicate all cells of the tumor. This concept of heterogeneity has led some investigators to propose a cancer stem cell model. As patients are treated with chemotherapy, most of the dividing cells are killed, but this leaves a small subset of cells that have the ability to remake the entire tumor. These are cancer stem cells. They possess the signals of self-renewal and yet can also differentiate. If one could understand more about the cells

Who reads Cancer Stem Cells: Methods and Protocols (Methods in Molecular Biology (568))?

Author

John S. Yu (editor)

Publisher

Springer

Published

2009

Language

EN

ISBN

9781597452809

Category

nonfiction

Subjects

Medical, Science, Biology