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Dynamic Modelling of Prosthetic Chorded Mitral Valves Using the Immersed Boundary Method by P.N. Watton; X.Y. Luo; X. Wang; G.M. Bernacca; P. Molloy; D.J. Wheatley is a Medicine article available to read on EtoBox.

What is Dynamic Modelling of Prosthetic Chorded Mitral Valves Using the Immersed Boundary Method about?

Current artificial heart valves either have limited lifespan or require the recipient to be on permanent anticoagulation therapy. In this paper, effort is made to assess a newly developed bileaflet valve prosthesis made of synthetic flexible leaflet materials, whose geometry and material properties are based on those of the native mitral valve, with a view to providing superior options for mitral valve replacement. Computational analysis is employed to evaluate the geometric and material design of the valve, by investigation of its mechanical behaviour and unsteady flow characteristics. The immersed boundary (IB) method is used for the dynamic modelling of the large deformation of the valve leaflets and the fluid-structure interactions. The IB simulation is first validated for the aortic prosthesis subjected to a hydrostatic loading. The predicted displacement fields by IB are compared with those obtained using ANSYS, as well as with experimental measurements. Good quantitative agreement is obtained. Moreover, known failure regions of aortic prostheses are identified. The dynamic behaviour of the valve designs is then simulated under four physiological pulsatile flows. Experimental

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Author

P.N. Watton; X.Y. Luo; X. Wang; G.M. Bernacca; P. Molloy; D.J. Wheatley

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0021-9290)

Published

2007

Language

EN

Field

Medicine (Health Sciences)