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Optical Rotation per Refractive Index Unit, or Enantiomeric (E) Factor, for Screening Enantioselective Catalysts Through Asymmetric Activation or Carbohydrates by Remy Angelaud; Yousuke Matsumoto; Toshinobu Korenaga; Kenichi Kudo; Masaaki Senda; Koichi Mikami is a Chemistry article available to read on EtoBox.

What is Optical Rotation per Refractive Index Unit, or Enantiomeric (E) Factor, for Screening Enantioselective Catalysts Through Asymmetric Activation or Carbohydrates about?

A super high-throughput screening (SHTS) system can be constructed by combining high-performance liquid chromatography (HPLC), optical rotation (OR), and refractive index unit (RIU) to determine not only the enantioselectivity of the addition of diethylzinc to an aliphatic aldehyde catalyzed by a binaphthol-zinc complex through asymmetric activation with chiral Schiff bases, but also the enantiopurity of a carbohydrate. The enantiomeric (e) factor, which we define here as optical rotation per refractive index unit, is linearly related to the percent enantiomeric excess (%ee) and is independent of concentration.

Who reads Optical Rotation per Refractive Index Unit, or Enantiomeric (E) Factor, for Screening Enantioselective Catalysts Through Asymmetric Activation or Carbohydrates?

Author

Remy Angelaud; Yousuke Matsumoto; Toshinobu Korenaga; Kenichi Kudo; Masaaki Senda; Koichi Mikami

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0899-0042)

Published

2000

Language

EN

Field

Chemistry (Physical Sciences)