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Clinical Significance of Postoperative Acute Pancreatitis After Pancreatoduodenectomy and Distal Pancreatectomy by Naoki Ikenaga; Takao Ohtsuka; Kohei Nakata; Yusuke Watanabe; Yasuhisa Mori; Masafumi Nakamura is a Medicine article available to read on EtoBox.

What is Clinical Significance of Postoperative Acute Pancreatitis After Pancreatoduodenectomy and Distal Pancreatectomy about?

Background The definition of postoperative acute pancreatitis as a specific complication of pancreatic surgery was proposed in 2016. Its presence and relevance have not been established, especially after a distal pancreatectomy. Methods Medical records of 319 patients who underwent pancreatoduodenectomy or distal pancreatectomy were analyzed. Postoperative acute pancreatitis was defined as an increase in serum amylase activity greater than the upper normal limit on postoperative day 1, according to Connor’s definition of postoperative acute pancreatitis. Results Postoperative acute pancreatitis occurred in 63.4% of 153 of the patients undergoing pancreatoduodenectomy and 65.7% of the 166 undergoing distal pancreatectomies. Patients who developed postoperative acute pancreatitis after pancreatoduodenectomy experienced an increase in the rate of morbidity (22.7% vs 7.1%; P = .0137), including postoperative pancreatic fistula (18.6% vs 1.8%; P = .024), resulting in greater postoperative stays (21 days vs 17 days; P = .0008). Postoperative acute pancreatitis in association with an increased serum C-reactive protein ≥18.0 mg/dL (which we defined as a clinically relevant postoperative ac

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Author

Naoki Ikenaga; Takao Ohtsuka; Kohei Nakata; Yusuke Watanabe; Yasuhisa Mori; Masafumi Nakamura

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)