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This systematic review evaluates the efficacy, tolerability, and biological mechanisms of photobiomodulation (PBM) for treating major depressive disorder (MDD). The findings suggest that red and near-infrared light can penetrate the skull and enhance mitochondrial metabolism, showing promising antidepressant effects comparable to traditional medications. However, the studies reviewed exhibit heterogeneity and lack appropriate controls, indicating a need for further research to establish optimal treatment pa

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streetpho96

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EN