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What is C. elegans LEM-3 Nuclease Functionality about?

The study investigates the role of the C. elegans LEM-3/ANKLE1 nuclease in processing DNA bridges during cell division, highlighting its importance for genome integrity. LEM-3 is shown to cleave various branched DNA structures and requires its LEM-like and GIY-YIG domains for activity and localization to the midbody. The findings suggest that LEM-3 acts as a critical

Author

sunliyu19760215

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EN