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Can I read An Approach for Evaluating the Effects of Dietary Fiber Polysaccharides on the Human Gut Microbiome and Plasma Proteome on EtoBox?
An Approach for Evaluating the Effects of Dietary Fiber Polysaccharides on the Human Gut Microbiome and Plasma Proteome by Omar Delannoy-Bruno; Chandani Desai; Juan J. Castillo; Garret Couture; Ruteja A. Barve; Vincent Lombard; Bernard Henrissat; Jiye Cheng; Nathan Han; David K. Hayashi; Alexandra Meynier; Sophie Vinoy; Carlito B. Lebrilla; Stacey Marion; Andrew C. Heath; Michael J. Barratt; Jeffrey I. Gordon is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is An Approach for Evaluating the Effects of Dietary Fiber Polysaccharides on the Human Gut Microbiome and Plasma Proteome about?
## Significance Dietary fibers contain complex mixtures of biomolecules, making it difficult to develop/test hypotheses about how different fiber-types impact different components of the human gut microbiome and how microbiome changes that they produce are linked to human physiology. Here, we analyze microbiome and plasma proteome responses to consumption of two fiber-enriched snacks in two human studies. We use a variety of computational methods to correlate their effects on gut microbiome genes encoding enzymes that degrade complex fiber-associated polysaccharides, the microbial products of polysaccharide degradation, and plasma proteins representing diverse physiological processes. This approach can be used to guide the design of fiber-containing snacks that more precisely manipulate microbiome features in ways that improve nutritional and health status.
Who reads An Approach for Evaluating the Effects of Dietary Fiber Polysaccharides on the Human Gut Microbiome and Plasma Proteome?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Omar Delannoy-Bruno; Chandani Desai; Juan J. Castillo; Garret Couture; Ruteja A. Barve; Vincent Lombard; Bernard Henrissat; Jiye Cheng; Nathan Han; David K. Hayashi; Alexandra Meynier; Sophie Vinoy; Carlito B. Lebrilla; Stacey Marion; Andrew C. Heath; Michael J. Barratt; Jeffrey I. Gordon
- Publisher
- Proceedings of the National Academy of Sciences
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)