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Brain Frailty Associated with Stroke Events in Anterior Circulation Large Artery Occlusion by Jing Tian; Kun Zhang; Junzhao Cui; Jin Qin; Binbin Wang; Lixia Zhou; Tong Li; Kailin Bu; Zhongzhong Li; Lin Liu; Qisong Wang; Si Yuan; Lina Ma; Ye Wang; Rui Wang; Chaoyue Meng; Biyi Zhou; Li Guo; Xiaoyun Liu is a Medicine article available to read on EtoBox.

What is Brain Frailty Associated with Stroke Events in Anterior Circulation Large Artery Occlusion about?

## Objective To investigate the factors associated with brain frailty and the effect of brain frailty in patients with anterior circulation large artery occlusion (AC-LAO). ## Methods 1100 patients with AC-LVO consecutively admitted to the Second Hospital of Hebei Medical University, North China between June 2016 and April 2018 were retrospectively analyzed. The variables associated with brain frailty and stroke outcome were analyzed by ANOVA analysis, the Mann-Whitney __U__ test and multiple linear regression. Based on previous research. Brain frailty score comprises 1 point each for white matter hyperintensity (WMH), old infarction lesions, and cerebral atrophy among 983 participants with baseline brain magnetic resonance imaging or computed tomography. ## Results Among AC-LAO participants, baseline brain frailty score ≥ 1 was common (750/983, 76.3%). Duration of hypertension > 5 years (mean difference [MD] 0.236, 95% CI 0.077, 0.395, __p__ = 0.004), multiple vessel occlusion (MD 0.339, 95% CI 0.068, 0.611, __p__ = 0.014) and basal ganglia infarction (MD -0.308, 95% CI -0.456, -0.160, __p__ < 0.001) were independently associated with brain frailty score. Brain frailty score was i

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Author

Jing Tian; Kun Zhang; Junzhao Cui; Jin Qin; Binbin Wang; Lixia Zhou; Tong Li; Kailin Bu; Zhongzhong Li; Lin Liu; Qisong Wang; Si Yuan; Lina Ma; Ye Wang; Rui Wang; Chaoyue Meng; Biyi Zhou; Li Guo; Xiaoyun Liu

Publisher

BioMed Central

Published

2024

Language

EN

Field

Medicine (Health Sciences)