Opening book details…
Can I read A Hydrophobic Starch Polymer for Nanoparticle-Mediated Delivery of Docetaxel on EtoBox?
A Hydrophobic Starch Polymer for Nanoparticle-Mediated Delivery of Docetaxel by Prajakta Dandekar; Ratnesh Jain; Thomas Stauner; Brigitta Loretz; Marcus Koch; Gerhard Wenz; Claus-Michael Lehr is a Materials Science article available to read on EtoBox.
What is A Hydrophobic Starch Polymer for Nanoparticle-Mediated Delivery of Docetaxel about?
## Abstract A hydrophobic starch derivative is used for safe and enhanced delivery of anticancer agents. The synthesis and characterization of propyl starch with a controlled degree of substitution to modulate the release of the encapsulated hydrophobic drug is reported. The application of this polymer for formulating nanoparticles of docetaxel, an anti‐cancer agent effective against numerous types of cancers but possessing intrinsic formulation difficulties is described. The solvent emulsification/diffusion technique is used and the synthesis is optimized with respect to several formulation parameters. Uptake studies with these nanoparticles indicate their enhanced internalization by the cancerous cells and their peri‐nuclear localization.magnified image
Who reads A Hydrophobic Starch Polymer for Nanoparticle-Mediated Delivery of Docetaxel?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Prajakta Dandekar; Ratnesh Jain; Thomas Stauner; Brigitta Loretz; Marcus Koch; Gerhard Wenz; Claus-Michael Lehr
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 1616-5187)
- Published
- 2011
- Language
- EN
- Field
- Materials Science (Physical Sciences)