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Antimicrobial Activity of Quinolone Derivatives by Piyushi Mishra is a document available to read on EtoBox.
What is Antimicrobial Activity of Quinolone Derivatives about?
The document discusses various quinolone antibiotics and how different substitutions on their core structure can impact their antimicrobial activity and properties. Fluoro substitutions at C-6 increase potency and lipophilicity, improving penetration. A cyclopropyl substitution at C-7 also increases potency. Ciprofloxacin is more potent than norfloxacin and ofloxacin.
- Author
- Piyushi Mishra
- Language
- EN