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Can I read Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines on EtoBox?
Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines by Abdallah Ladaycia; Brigitta Loretz; Catherine Passirani; Claus-Michael Lehr; Elise Lepeltier is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines about?
Nanomedicine implication in cancer treatment and diagnosis studies witness huge attention, especially with the promising results obtained in preclinical studies. Despite this, only few nanomedicines succeeded to pass clinical phase. The human microbiota plays obvious roles in cancer development. Nanoparticles have been successfully used to modulate human microbiota and notably tumor associated microbiota. Taking the microbiota involvement under consideration when testing nanomedicines for cancer treatment might be a way to improve the poor translation from preclinical to clinical trials. Co-culture models of bacteria and cancer cells, as well as animal cancer-microbiota models offer a better representation for the tumor microenvironment and so potentially better platforms to test nanomedicine efficacy in cancer treatment. These models would allow closer representation of human cancer and might smoothen the passage from preclinical to clinical cancer studies for nanomedicine efficacy.
Who reads Microbiota and cancer: In vitro and in vivo models to evaluate nanomedicines?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Abdallah Ladaycia; Brigitta Loretz; Catherine Passirani; Claus-Michael Lehr; Elise Lepeltier
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)