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Exercise and Urtica Dioica extract ameliorate mitochondrial function and the expression of cardiac muscle Nuclear Respiratory Factor 2 and Peroxisome proliferator-activated receptor Gamma Coactivator 1-alpha in STZ-induced diabetic rats by Seyyedeh Masoumeh Seyydi,Asghar Tofighi,Masoud Rahmati,Javad Tolouei Azar is a nonfiction available to read on EtoBox.

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Gene, 822 (2022) 146351. doi:10.1016/j.gene.2022.146351 Exercise and Urtica Dioica extract ameliorate mitochondrial function and the expression of cardiac muscle Nuclear Respirato ... 1 1 Introduction 2 2 Materials and methods 2 2.1 Animals 2 2.2 Induction of diabetes 2 2.3 Gathering the plant and preparing the extract 2 2.4 Treadmill exercise 3 2.5 Tissue preparation 3 2.6 Western blot analysis 3 2.7 Echocardiography 3 2.8 Determining ATP content 3 2.9 Determining citrate synthase (CS) activity 3 2.10 Statistical analysis 3 3 Results 3 3.1 EX + UD treatment ameliorates diabetes-induced BW loss and decreases FBG in STZ-induced diabetic rats. 3 3.2 EX + UD treatment attenuates diabetes-related cardiac dysfunction in STZ-induced diabetic rats. 3 3.3 EX + UD treatment improves mitochondrial function in the cardiac muscle of STZ-induced diabetic rats. 4 3.4 EX + UD treatment improves NRF2 and PGC-1α deficits in the cardiac muscle of STZ-induced diabetic rats. 5 4 Discussion 5 5 Conclusion 6 CRediT authorship contribution statement 6 Declaration of Competing Interest 6 Acknowledgments 6 References 6 Exercise,Urtica Dioica,PGC1α,NRF2,Heart,Diabetes

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Author

Seyyedeh Masoumeh Seyydi,Asghar Tofighi,Masoud Rahmati,Javad Tolouei Azar

Publisher

Elsevier B.V.

Language

EN

Category

nonfiction