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1) The study evaluated using tumor hypoxia levels measured by PET scans to determine the appropriate dose of chemoradiotherapy for HPV-related oropharyngeal cancer patients. 2) 158 patients received either a reduced 30 Gy dose if their tumor was found to be nonhypoxic, or the standard 70 Gy dose if hypoxic. For patients receiving 30 Gy, the 2-year locoregional control rate was 94.7%, meeting the primary objective. Acute side effects were less common in the 30 Gy group. 3) Tumor hypoxia shows promise as a m

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