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Can I read Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review on EtoBox?
Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review by Timur Liwinski; Undine E. Lang is a Medicine article available to read on EtoBox.
What is Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review about?
Depressive disorders pose significant challenges to global public health, necessitating effective prevention and management strategies. Notably, the occurrence of suicide frequently coincides with depressive episodes. Suicide is as a paramount global health concern that demands efficacious preventive strategies. Current psychiatric approaches heavily rely on pharmacological interventions but have had limited success in addressing the global burden of mental health issues. Suboptimal nutrition, with its impact on the neuroendocrine system, has been implicated in the underlying pathology of depressive disorders. Folate, a group of water-soluble compounds, plays a crucial role in various central nervous system functions. Depressed individuals often exhibit low levels of serum and red blood cell folate. Multiple studies and systematic reviews have investigated the efficacy of folic acid and its derivative, L-methylfolate, which can cross the blood–brain barrier, as stand-alone or adjunct therapies for depression. Although findings have been mixed, the available evidence generally supports the use of these compounds in depressed individuals. Recent studies have established links between
Who reads Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Timur Liwinski; Undine E. Lang
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)