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This study presents the development and validation of a paper spray mass spectrometry (PS-MS/MS) method for the rapid quantification of remdesivir and its active metabolite, GS-441524, in human plasma. The method demonstrated excellent linearity, precision, and accuracy, with no sample preparation required, making it suitable for clinical pharmacokinetics and therapeutic drug monitoring. The findings highlight the potential of PS-MS/MS technology to improve the analysis of antiviral drugs during the COVID-1

Author

idesk41

Language

EN