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Sustained Subconjunctival Drug Delivery Systems: Current Trends and Future Perspectives by Fojan Rafiei; Hadi Tabesh; Farrokh Farzad is a Medicine article available to read on EtoBox.

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## Purpose: One of the challenges of ocular drug delivery systems is sustainable delivery of the intended drug to the posterior segment of the eye. periocular routes of drug delivery are a promising method to bridge this challenge. the purpose of this study is to investigate the recent advances and potentials of subconjunctival route and its pros and cons in comparison with other ocular drug delivery routes. ## Methods: In this literature review, the comprehensive search of publications was performed in medline/pubmed indicating investigations on subconjunctival drug delivery systems using relevant keywords. ## Results: Based on the resultant detailed criteria to choose an appropriate ocular drug delivery route, it is revealed that most of these routes are either highly invasive and/or provide low bioavailability of drug to the target tissue. nevertheless, subconjunctival drug delivery could be considered as one of the less invasive and easily accessible routes for delivering various drugs to both anterior and posterior segments of the eye. however, most of such researches are at the stage of animal study in their pipelines. ## Conclusion: Periocular route of drug delivery is one o

Who reads Sustained Subconjunctival Drug Delivery Systems: Current Trends and Future Perspectives?

Author

Fojan Rafiei; Hadi Tabesh; Farrokh Farzad

Publisher

Springer Netherlands; Springer-Verlag; Kluwer Academic Publishers; Springer Science and Business Media LLC (ISSN 0165-5701)

Published

2020

Language

EN

Field

Medicine (Health Sciences)