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The study investigates the effects of Polyphyllin II (PPII) on hepatocellular carcinoma (HCC) cells, revealing that PPII induces pyroptosis, a pro-inflammatory type of programmed cell death, through the NLRP3/Caspase-1/GSDMD signaling pathway. PPII treatment leads to increased oxidative stress and the release of inflammatory cytokines, effectively inhibiting HCC cell growth in vitro and in vivo without significant side effects. These findings suggest that PPII could serve as a potential therapeutic agent fo

Author

akash.me.en12

Language

EN