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Can I read Immunohistochemical Study of Melanocytic Nevus and Malignant Melanoma with Monoclonal Antibodies Against S-100 Subunits on EtoBox?
Immunohistochemical Study of Melanocytic Nevus and Malignant Melanoma with Monoclonal Antibodies Against S-100 Subunits by Kwang Hyun Cho; Ken Hashimoto; Yoshiki Taniguchi; Teresa Pietruk; Richard J. Zarbo; Teisa An is a Medicine article available to read on EtoBox.
What is Immunohistochemical Study of Melanocytic Nevus and Malignant Melanoma with Monoclonal Antibodies Against S-100 Subunits about?
Immunohistochemical localization of S-100 protein a and B subunits in the cells of melanocytic nevi and malignant melanomas was studied by using monoclonal antibodies directed against each subunit. Although polyclonal anti-S-100 reactivities have been demonstrated uniformly in all nevus cells and melanoma cells, monoclonal anti-S-100a and anti-S-10oB reactivities were either absent or rarely found in ordinary junctional nevi or junctional nests of ordinary compound nevi. However, in the junctional nests of dysplastic junctional nevi and junctional components of dysplastic compound nevi, monoclonal anti-S-100a reactivity become more frequent, whereas monoclonal anti-S-1008 reactivity remains negative. In the superficial variety of melanomas such as superficial spreading melanoma and lentigo maligna melanoma, monoclonal anti-S-100B is nonreactive until vertical growth or invasiveness begins. Most nodular melanomas are positively stained with both monoclonal anti-S-100a and anti-S-100@. It is suggested that monoclonal anti-S-100a can be an indicator of active junctional nevus of melanocytic nevi and the reactivity with monoclonal anti-S-100B may be related to vertical progression of s
Who reads Immunohistochemical Study of Melanocytic Nevus and Malignant Melanoma with Monoclonal Antibodies Against S-100 Subunits?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Kwang Hyun Cho; Ken Hashimoto; Yoshiki Taniguchi; Teresa Pietruk; Richard J. Zarbo; Teisa An
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 1990
- Language
- EN
- ISBN
- 9782820660428
- Field
- Medicine (Health Sciences)