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Sites of Local Recurrence After Surgery, with or Without Chemotherapy, for Rectal Cancer: Implications for Radiotherapy Field Design by George Hruby; Michael Barton; Sharon Miles; Susan Carroll; Elias Nasser; Graham Stevens is a Medicine article available to read on EtoBox.

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## Purpose: To examine the sites of pelvic recurrence in patients with rectal cancer previously untreated with radiotherapy to determine the relative frequency and location of recurrence within the pelvis. ## Methods and materials: The records of patients with locally recurrent rectal cancer referred to three radiation oncology departments between 1984 and 1997 were reviewed. the data collected included the date and type of the initial resection and the pathologic findings. the site of recurrence within the pelvis, presence of metastasis, and date of recurrence were documented. ## Results: A total of 269 patients were included. tumor had invaded through the muscularis in 74% and involved other organs in 9%. fifty-two percent of patients were node positive at initial surgery. the median time to local recurrence from surgery was 18 months (range 15-20) and from local recurrence to death was 14 months (range 12-17). both the initial tumor stage and the resection type influenced the recurrence location within the pelvis (p <0.01). t4 tumors comprised only 9% of initial t stage tumors but accounted for 38% of anterior central pelvic recurrences (p <0.01). all perineal recurrences occurr

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Author

George Hruby; Michael Barton; Sharon Miles; Susan Carroll; Elias Nasser; Graham Stevens

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2003

Language

EN

Field

Medicine (Health Sciences)