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Polymyxins Inhibit NDH-2 in Gram-Negatives by Thiago Willian Correia Pereira is a document available to read on EtoBox.

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The document examines the ability of polymyxin B and colistin to inhibit NADH-quinone oxidoreductases (NDH-2) in Gram-negative bacteria. It finds that polymyxin B and colistin inhibit NDH-2 activity in a concentration-dependent manner for three bacterial species. The mechanism of inhibition by polymyxin B in E. coli is also investigated and conforms to mixed and non-competitive inhibition models.

Author
Thiago Willian Correia Pereira
Language
EN