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Myasthenia gravis is an autoimmune disease where antibodies attack acetylcholine receptors in the neuromuscular junction, causing muscle weakness. The document discusses the role of the thymus gland in the pathogenesis of the disease and the implications of thymectomy. In anti-acetylcholine receptor antibody-positive patients without thymoma, abnormal germinal center formation in the thymus plays a key role by facilitating the production and maturation of disease-causing antibodies. Thymectomy may help term
- Author
- Helen Sobczyk
- Language
- EN