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This document summarizes a study on the interaction of cisplatin and carboplatin with sodium thiosulfate. The study found: 1) Cisplatin and carboplatin disappeared more rapidly in solutions containing therapeutic concentrations of sodium thiosulfate, with half-lives of 66 minutes for cisplatin and 537 minutes for carboplatin. 2) At higher thiosulfate concentrations found in urine, the half-lives were much shorter: 3.7 minutes for cisplatin and 33.8 minutes for carboplatin. 3) Reaction products of cispl
- Author
- Nur Asmaulhusnah
- Language
- EN