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Can I read Anaphylactoid Reaction to High‐dose Methotrexate and Successful Desensitization on EtoBox?
Anaphylactoid Reaction to High‐dose Methotrexate and Successful Desensitization by Ignacio Oulego‐Erroz; Mercedes Maneiro‐Freire; Marta Bouzón‐Alejandro; Manuel Vázquez‐Donsión; José Miguel Couselo is a Medicine article available to read on EtoBox.
What is Anaphylactoid Reaction to High‐dose Methotrexate and Successful Desensitization about?
## Abstract Anaphylactic/anaphylactoid reaction to methotrexate (MTX) is uncommon. It may occur with the first dose (non‐allergic reactions) or after a previous exposure to the drug (allergic or specific reactions). Desensitization has been shown effective in children with allergic‐type reactions permitting the continuation of high‐dose methotrexate (HDMTX) therapy. We report the case of a child with localized osteosarcoma who developed an anaphylactoid reaction after a first HDMTX course. A desensitization protocol was successfully applied allowing the administration of four additional courses. In our experience, desensitization can be a safe and effective procedure in children with anaphylactoid reactions to HDMTX. Pediatr Blood Cancer. 2010;55:557–559. © 2010 Wiley‐Liss, Inc.
Who reads Anaphylactoid Reaction to High‐dose Methotrexate and Successful Desensitization?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ignacio Oulego‐Erroz; Mercedes Maneiro‐Freire; Marta Bouzón‐Alejandro; Manuel Vázquez‐Donsión; José Miguel Couselo
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)