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Polyether antibiotics : naturally occurring acid ionophores by John W. Westley is a nonfiction available to read on EtoBox.

What is Polyether antibiotics : naturally occurring acid ionophores about?

This collection of essays will stimulate the use of ionophores in different research areas. It includes information on potential breakthroughs in the halogenated derivatives of lasalocid and ethers of antibiotic A204A, polyethers and analytical techniques used to unravel their complex structures. Cover 1 Half Title 3 Title Page 5 Copyright Page 6 Table of Contents 11 Foreword 7 Preface 9 List of Contributors 13 Contents of Volume 1—Biology 15 1. Chemical Synthesis 19 I. Introduction 20 II. Synthetic Methods 20 A. β-Hydroxy Ketone 20 B. Spiroketal 21 C. Tetrahydrofurans 27 D. Tetrahydropyrans 30 E. 1,2-Stereochemistry 31 F. Chiral Starting Materials 33 III. Total Syntheses 33 A. A23187 (Calcimycin) 33 B. Evans Synthesis 33 C. Grieco Synthesis 35 D. Ogawa Synthesis 38 E. Lasalocid A (X-537A) 38 F. Kishi Synthesis 38 G. Ireland Synthesis 45 H. Monesin 48 I. Kishi Synthesis 48 J. Still Synthesis 56 References 64 Bibliography 66 2. Chemical Transformations of Polyether Antibiotics 69 I. Introduction 69 II. Lasalocid 70 A. Chemical Modifications 70 B. Biological Activity 81 III. Monensin and Dianemycin 84 IV. Nigericin and X-206 86 V. Antiobiotic A204 88 A. Chemical Modifications 88 B. B

Who reads Polyether antibiotics : naturally occurring acid ionophores?

Author

John W. Westley

Publisher

CRC Press, Taylor & Francis Group

Published

2023

Language

EN

ISBN

9780824716554

Category

nonfiction

Subjects

Science, Chemistry, Medical

Updated

2026-03-24