About this document
Mechanistic Model for rAAV Production by huang.wkang is a document available to read on EtoBox.
This article presents a mechanistic model for the production dynamics of recombinant adeno-associated virus (rAAV) using the baculovirus expression vector system (BEVS). The model identifies key bottlenecks in rAAV production, particularly vector genome amplification, and validates its predictions against experimental data. The findings suggest that BEVS can improve rAAV manufacturing efficiency, addressing the high costs and low yields currently faced in gene therapy production.
- Author
- huang.wkang
- Language
- EN