Can I read The Impact of Stage and Histology on the Long-term Clinical Course of 163,808 Patients with Breast Carcinoma on EtoBox?

The Impact of Stage and Histology on the Long-term Clinical Course of 163,808 Patients with Breast Carcinoma by John W. Gamel; John S. Meyer; Eric Feuer; Barry A. Miller is a Medicine article available to read on EtoBox.

What is The Impact of Stage and Histology on the Long-term Clinical Course of 163,808 Patients with Breast Carcinoma about?

## BACKGROUND. Stage and histologic type have a significant impact on the long term clinical course of breast carcinoma. Clinical course is governed by two components: likelihood of cure and median tumor-related survival time among uncured patients. Estimates of these components can be derived only by using survival models that incorporate cured fraction as a specific parameter. ## METHODS. The prognostic value of stage and histologic type was determined for 163,808 patients with breast carcinoma using the log normal and log logit curebased survival models. Follow-up ranged from 1 month to 19 years and was obtained from the SEER Program. ## RESULTS. In approximate terms, ductal carcinoma was diagnosed in 70% of the patients, with estimated cured fractions of 2/3 and 113 for local, and regional disease, respectively. Estimates of median survival times for uncured patients were 10 and 5 years. Findings were similar for patients with tumors of miscellaneous histologic types. For patients with medullary carcinoma, cured fractions were relatively high at 82% and 64%, but median survival times were relatively short at 4 and 3 years. Corresponding values for patients with invasive comedo

Who reads The Impact of Stage and Histology on the Long-term Clinical Course of 163,808 Patients with Breast Carcinoma?

Author

John W. Gamel; John S. Meyer; Eric Feuer; Barry A. Miller

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1996

Language

EN

Field

Medicine (Health Sciences)