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Hyperfine structure in melting profile of bacteriophage lambda DNA by Osamu Gotoh; Yuzuru Husimi; Sadato Yabuki; Akiyoshi Wada is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Hyperfine structure in melting profile of bacteriophage lambda DNA about?

## Abstract A high‐resolution plotter of differential melting profiles of DNA, RNA, or related biopolymers with an on‐line mini‐computer is described. With this device, more than 15 transition steps were identified in the thermal melting profile of DNA from bacteriophage lambda. These fine structures were found to be reproducible, and some of them disappear in the deletion mutant. To Examine the melting profile, computer simulations for several hypothetical polynucleotide sequences were performed, and compared with experimental data. The sharp peaks that appeared in the differential melting profile of λ DNA may come from some homogeneous sequences of 500 bases or longer.

Who reads Hyperfine structure in melting profile of bacteriophage lambda DNA?

Author

Osamu Gotoh; Yuzuru Husimi; Sadato Yabuki; Akiyoshi Wada

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0006-3525)

Published

1976

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)