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Can I read Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin on EtoBox?
Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin by Soheyla Karimi; Hassan Namazi is a Materials Science article available to read on EtoBox.
What is Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin about?
In the present study, a novel magnetic carbon modified with 3-aminopropyltrimethoxysilane (APTMS) using maltose disaccharide molecule as a green capping agent, and a third-generation triazine dendrimer (FeO@C@TD-G3) was then covalently attached to their surface. Eventually, FeO@C@TD-G3 was reacted with graphene quantum dots (GQDs) for the preparation of final FeO@C@TDGQDs microspheres. The obtained compound was successfully applied as a novel magnetic carrier for the Doxorubicin (DOX) drug delivery. Various techniques such as Fourier transform infrared (FT-IR), X-ray diffraction (XRD), Zeta potential, Ultraviolet-visible (UV-vis), Atomic force microscopy (AFM), Scanning electron microscopy (SEM), Energy-dispersive X-ray (EDX), Brunauer-Emmett-Teller (BET), Vibration sample magnetometer (VSM), and Fluorescence and Photoluminescence (PL) analysis were used to approve the synthesis of microspheres. Drug release studies carried out at different pHs (pH 5, 6.8 and 7.4) and the cytotoxic assay was evaluated for DOX-loaded FeO@C@TDGQDs against Human lung cancer cell lines (A549). The drug release assay showed that the amount of the DOX release from dendrimer was noticeably pH depended. In
Who reads Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Soheyla Karimi; Hassan Namazi
- Publisher
- Elsevier BV
- Published
- 2020
- Language
- EN
- Field
- Materials Science (Physical Sciences)