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Can I read Distinction between isolated tumor cells and micrometastases in breast cancer : Is it reliable and useful? on EtoBox?
Distinction between isolated tumor cells and micrometastases in breast cancer : Is it reliable and useful? by Isabelle de Mascarel; Gaetan MacGrogan; Marc Debled; Veronique Brouste; Louis Mauriac is a Medicine article available to read on EtoBox.
What is Distinction between isolated tumor cells and micrometastases in breast cancer : Is it reliable and useful? about?
## Abstract ## BACKGROUND In routine practice, the distinction between isolated tumor cells (ITC) and micrometastases (MIC) in patients with breast cancer is sometimes difficult to discern. The authors assessed differences in classifying patients according to the American Joint Commission on Cancer (AJCC) and the International Union Against Cancer (UICC) definitions and method of sizing. ## METHODS We assessed the characteristics of metastatic deposits in only 1 involved lymph node in 337 patients with operable breast cancer (median follow‐up, 15.3 years). When sizing multiple clusters, either the diameter of the area with close clusters (Method 1) or the size of the largest cluster (Method 2) was taken into account. Patients were classified and their survival was assessed according to the 2 sizing methods and the criteria used for definitions (size in AJCC; size and topography in UICC). ## RESULTS With the AJCC definitions, 32 patients would be differently classified according to the method of sizing. With the UICC definitions, some patients with parenchymal ITC would be classified as pN1mi, 38 by Method 1 and 53 by Method 2. Some pathologists would classify the 66 patients who ha
Who reads Distinction between isolated tumor cells and micrometastases in breast cancer : Is it reliable and useful??
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Isabelle de Mascarel; Gaetan MacGrogan; Marc Debled; Veronique Brouste; Louis Mauriac
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)