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What is Appel and Mitsunobu Reactions Explained about?
The document summarizes several phosphorus-based organic reactions: 1) The Appel reaction converts alcohols to alkyl halides using triphenylphosphine and tetrahalomethanes under mild conditions with high yields. 2) The Mitsunobu reaction converts alcohols to other functional groups like esters using triphenylphosphine and azodicarboxylates, inverting stereochemistry. 3) The Wittig-Horner reaction produces olefins from aldehydes or ketones reacted with stabilized phosphorus ylides with excellent E sele
- Author
- Ricardo Doroteo
- Language
- EN